Welcome Carmen
Welcome our new visiting imaging research intern - Carmen joins us as a visiting research intern with wealth of experience in science education and held an undergraduate chemistry degree from Research Sch of Chem at ANU.
Abstract Accepted!
Congrats to Harry, Tienan, Daniel, Yujie and Avinash for their abstract accepted at microTAS. Venturing into microfluidic fluidics with advanced imaging
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Towards personalized thrombosis studies: in situ Mold-free Lithography of Physiological Stenosis in Circular Capillaries- Daniel Lim
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Inexpensive Immersive Display for 3D Imaging Flow Assays - Harry and Avinash
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Quantification of Thrombus Kinetics through inhibiting receptor shedding with label-free imaging flow assay, Yujie Zheng
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Computational Single Objective lightsheet microscopy for Imaging microfluidics - Tienan Xu
New cohort of Imaging Scientist/Technician in oBIG lab
Welcome a new cohort of Imaging researchers to the team.
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Mr Zhiduo Zhang is joining us as an Imaging Scientist and also pursuing MPhil in Bioimage Informatics
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Mr Junxiang Zhang is joining us as an Imaging Technician
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Mr Hanqi Lin is joining us as an Imaging Technician
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Mr Jasper Li is joining us as a Imaging Technician (with focus on Platelet Biology)
Completion of Phase 1 of R&D of Compact PolyScope system with Trendbio Pty Ltd under AusIndustry Innovation Connection grant scheme. Look forward to Phase 2 and 3 of product development.
Steve will serve on the Advisory Editorial Board of Biomicrofluidics-AIP.
Droplet lens paper made to Top 10 cited - Biomedical Optics Devices, in Biomed Optics Express, in the last decade.
Janelia’s Optical Interest Group teams up with John Curtin School of Medical Research (ANU) for a monthly optical educational series, aiming to provide a unique opportunity to learn cutting-edge optical microscope technology and translational biology and medical applications. This series divides into Optics & technology, Optics & Biology, and Optics & Disease. Each Lecture contains the presentation and dedicated Q&A session. Open to all Janelians and Australia Biomedical Groups (ANU, University of Adelaide, UQ, UWA, UNSW, Monash, and Garvan) and beyond.
Imaging collaboration with Phan Lab at Garvan on Osteoclast. By intravital imaging, we reveal that RANKL-stimulated osteoclasts have an alternative cell fate in which they fission into daughter cells called osteomorphs. Inhibiting RANKL blocked this cellular recycling and resulted in osteomorph accumulation.
New portable technology that visualises clots forming in flowing blood in a 3D holographic livestream promises to dramatically improve screening and treatment of stroke, heart attack and coronavirus-induced lung failure.
COSI maps temporal dynamics of adhesive platelets and changing thrombus mass and highlights roles for actin polymerization and metalloproteinase activity in thrombus evolution and stabilization. COSI demonstrates the potential for real-time label-free quantification of flow-dependent adhesive events for biological structure of varying dry mass. COSI highlights the power of combining traditional phase imaging and backscattered imaging for microfluidic
assays and here, unpicks intra-thrombus mass and adhesive platelet-only activity events to picogram and sub-micrometer precision with millisecond time resolution under fluid shear stress.
A 3-photon imaging system for deep live imaging. This project aims to establish Australia’s first 3-photon microscope system with adaptive optics for deep intravital imaging. This advanced imaging system will enable researchers to investigate the biology of cells and tissue structures in a wide range of organs and engineered tissues, to a degree not possible with existing technology
Toyota Graduate program
Congratulations to Tao, Lab Technician since 2017 who have been accepted at the Toyota Graduate Training Program.
Our research program (Lee Group) has now matured from imaging tool development to translational imaging. Now our research activities seek to apply our host of advanced biofluidic imaging tools to study the biological fluidic force (vasculature and microfluidics) that governs cellular activities within their natural microenvironment with potential to reach into field of Immunology, Oncology and Mechano-biology
The rapid interactions of circulating human blood platelets is critical to prevent bleeding, but can cause thrombotic diseases (heart attack, stroke). These highly regulated interactions involve specific adhesive proteins. Our studies will define factors regulating platelet interactions. Imaging the thrombotic process will quantify platelet function at an unprecedented resolution and we have a panel of new candidate reagents that will be assessed for antithrombotic potential.
